MITF protects against oxidative damage-induced retinal degeneration by regulating the NRF2 pathway in the retinal pigment epithelium

Oxidative damage is one of the major contributors to retinal degenerative diseases such as age-related macular degeneration (AMD), while RPE mediated antioxidant defense plays an important role in preventing retinopathies. However, the regulatory mechanisms of antioxidant signaling in RPE cells are...

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Dades bibliogràfiques
Publicat a:Redox Biol
Autors principals: Han, Shuxian, Chen, Jianjun, Hua, Jiajia, Hu, Xiaojuan, Jian, Shuhui, Zheng, Guoxiao, Wang, Jing, Li, Huirong, Yang, Jinglei, Hejtmancik, J. Fielding, Qu, Jia, Ma, Xiaoyin, Hou, Ling
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2020
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7191850/
https://ncbi.nlm.nih.gov/pubmed/32361183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101537
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