Cargando...

Bisretinoid-mediated Complement Activation on Retinal Pigment Epithelial Cells Is Dependent on Complement Factor H Haplotype

Age-related macular degeneration (AMD) is a common central blinding disease of the elderly. Homozygosity for a sequence variant causing Y402H and I62V substitutions in the gene for complement factor H (CFH) is strongly associated with risk of AMD. CFH, secreted by many cell types, including those of...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Radu, Roxana A., Hu, Jane, Jiang, Zhichun, Bok, Dean
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979386/
https://ncbi.nlm.nih.gov/pubmed/24550392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.548669
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!