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Dual functionality of cis-regulatory elements as developmental enhancers and Polycomb response elements

Developmental gene expression is tightly regulated through enhancer elements, which initiate dynamic spatio–temporal expression, and Polycomb response elements (PREs), which maintain stable gene silencing. These two cis-regulatory functions are thought to operate through distinct dedicated elements....

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Dettagli Bibliografici
Pubblicato in:Genes Dev
Autori principali: Erceg, Jelena, Pakozdi, Tibor, Marco-Ferreres, Raquel, Ghavi-Helm, Yad, Girardot, Charles, Bracken, Adrian P., Furlong, Eileen E.M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2017
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5393054/
https://ncbi.nlm.nih.gov/pubmed/28381411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.292870.116
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