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Highly rearranged chromosomes reveal uncoupling between genome topology and gene expression
Chromatin topology is intricately linked to gene expression, yet its functional requirement remains unclear. Here, we comprehensively assessed the interplay between genome topology and gene expression using highly rearranged chromosomes (balancers) spanning ~75% of the Drosophila genome. Using trans...
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| Publicado no: | Nat Genet |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7116017/ https://ncbi.nlm.nih.gov/pubmed/31308546 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-019-0462-3 |
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