Chromosome topology guides the Drosophila Dosage Compensation Complex for target gene activation

X chromosome dosage compensation in Drosophila requires chromosome‐wide coordination of gene activation. The male‐specific lethal dosage compensation complex (DCC) identifies and binds to X‐chromosomal high‐affinity sites (HAS) from which it boosts transcription. A sub‐class of HAS, PionX sites, rep...

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Publicat a:EMBO Rep
Autors principals: Schauer, Tamás, Ghavi‐Helm, Yad, Sexton, Tom, Albig, Christian, Regnard, Catherine, Cavalli, Giacomo, Furlong, Eileen EM, Becker, Peter B
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5623837/
https://ncbi.nlm.nih.gov/pubmed/28794204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201744292
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