Chromosome topology guides the Drosophila Dosage Compensation Complex for target gene activation

X chromosome dosage compensation in Drosophila requires chromosome‐wide coordination of gene activation. The male‐specific lethal dosage compensation complex (DCC) identifies and binds to X‐chromosomal high‐affinity sites (HAS) from which it boosts transcription. A sub‐class of HAS, PionX sites, rep...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Schauer, Tamás, Ghavi‐Helm, Yad, Sexton, Tom, Albig, Christian, Regnard, Catherine, Cavalli, Giacomo, Furlong, Eileen EM, Becker, Peter B
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5623837/
https://ncbi.nlm.nih.gov/pubmed/28794204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201744292
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