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Dual functionality of cis-regulatory elements as developmental enhancers and Polycomb response elements

Developmental gene expression is tightly regulated through enhancer elements, which initiate dynamic spatio–temporal expression, and Polycomb response elements (PREs), which maintain stable gene silencing. These two cis-regulatory functions are thought to operate through distinct dedicated elements....

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Erceg, Jelena, Pakozdi, Tibor, Marco-Ferreres, Raquel, Ghavi-Helm, Yad, Girardot, Charles, Bracken, Adrian P., Furlong, Eileen E.M.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5393054/
https://ncbi.nlm.nih.gov/pubmed/28381411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.292870.116
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