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Differential regulation of hepatitis B virus core protein expression and genome replication by a small upstream open reading frame and naturally occurring mutations in the precore region

Hepatitis B virus (HBV) transcribes two subsets of 3.5-kb RNAs: precore RNA for hepatitis B e antigen (HBeAg) expression, and pregenomic RNA for core and P protein translation as well as genome replication. HBeAg expression could be prevented by mutations in the precore region, while an upstream ope...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Virology
Päätekijät: Zong, Li, Qin, Yanli, Jia, Haodi, Ye, Lei, Wang, Yongxiang, Zhang, Jiming, Wands, Jack R, Tong, Shuping, Li, Jisu
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5391676/
https://ncbi.nlm.nih.gov/pubmed/28260621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2017.02.020
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