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Point Mutations Upstream of Hepatitis B Virus Core Gene Affect DNA Replication at the Step of Core Protein Expression

The pregenomic RNA directs replication of the hepatitis B virus (HBV) genome by serving both as the messenger for core protein and polymerase and as the genome precursor following its packaging into the core particle. RNA packaging is mediated by a stem-loop structure present at its 5′ end designate...

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Bibliografische gegevens
Hoofdauteurs: Guarnieri, Michael, Kim, Kyun-Hwan, Bang, Genie, Li, Jisu, Zhou, Yonghong, Tang, Xiaoli, Wands, Jack, Tong, Shuping
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2006
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346833/
https://ncbi.nlm.nih.gov/pubmed/16378961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.2.587-595.2006
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