Point Mutations Upstream of Hepatitis B Virus Core Gene Affect DNA Replication at the Step of Core Protein Expression

The pregenomic RNA directs replication of the hepatitis B virus (HBV) genome by serving both as the messenger for core protein and polymerase and as the genome precursor following its packaging into the core particle. RNA packaging is mediated by a stem-loop structure present at its 5′ end designate...

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Detalhes bibliográficos
Main Authors: Guarnieri, Michael, Kim, Kyun-Hwan, Bang, Genie, Li, Jisu, Zhou, Yonghong, Tang, Xiaoli, Wands, Jack, Tong, Shuping
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346833/
https://ncbi.nlm.nih.gov/pubmed/16378961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.2.587-595.2006
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