Hepatitis B Virus Genotype C Isolates with Wild-Type Core Promoter Sequence Replicate Less Efficiently than Genotype B Isolates but Possess Higher Virion Secretion Capacity

Infection by hepatitis B virus (HBV) genotype C is associated with a prolonged viremic phase, delayed hepatitis B e antigen (HBeAg) seroconversion, and an increased incidence of liver cirrhosis and hepatocellular carcinoma compared with genotype B infection. Genotype C is also associated with the mo...

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Detalhes bibliográficos
Main Authors: Qin, Yanli, Tang, Xiaoli, Garcia, Tamako, Hussain, Munira, Zhang, Jiming, Lok, Anna, Wands, Jack, Li, Jisu, Tong, Shuping
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196399/
https://ncbi.nlm.nih.gov/pubmed/21775451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00819-11
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