Impaired Virion Secretion by Hepatitis B Virus Immune Escape Mutants and Its Rescue by Wild-Type Envelope Proteins or a Second-Site Mutation

Hepatitis B virus immune escape mutants have been associated with vaccine failure and reinfection of grafted liver despite immune prophylaxis, but their biological properties remain largely unknown. Transfection of 20 such mutants in a human hepatoma cell line identified many with severe impairment...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Kwei, Karen, Tang, Xiaoli, Lok, Anna S., Sureau, Camille, Garcia, Tamako, Li, Jisu, Wands, Jack, Tong, Shuping
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2013
Témata:
Structure and Assembly
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3571463/
https://ncbi.nlm.nih.gov/pubmed/23221548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02701-12
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky