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Impaired Virion Secretion by Hepatitis B Virus Immune Escape Mutants and Its Rescue by Wild-Type Envelope Proteins or a Second-Site Mutation

Hepatitis B virus immune escape mutants have been associated with vaccine failure and reinfection of grafted liver despite immune prophylaxis, but their biological properties remain largely unknown. Transfection of 20 such mutants in a human hepatoma cell line identified many with severe impairment...

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מידע ביבליוגרפי
Main Authors: Kwei, Karen, Tang, Xiaoli, Lok, Anna S., Sureau, Camille, Garcia, Tamako, Li, Jisu, Wands, Jack, Tong, Shuping
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2013
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3571463/
https://ncbi.nlm.nih.gov/pubmed/23221548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02701-12
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