Prevalence of Basal Core Promoter and Precore Mutations in Chinese Chronic Hepatitis B Patients and Correlation With Serum HBeAg Titers

The A1762T and G1764A mutations in the basal core promoter (BCP) region and the G1896A mutation in the precore (PC) region of hepatitis B virus (HBV) genome are found commonly in HBeAg-negative patients. Experiments in vitro suggest that BCP and PC mutation reduce and abolish HBeAg expression, respe...

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Vydáno v:J Med Virol
Hlavní autoři: Qin, Yanli, Zhang, Jiming, Mao, Richeng, Guo, Hongying, Yin, Youkuan, Wu, Xianghui, Weng, Xinhua, Wands, Jack, Tong, Shuping
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6329877/
https://ncbi.nlm.nih.gov/pubmed/19319958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jmv.21439
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