Deep sequencing of hepatitis B virus basal core promoter and precore mutants in HBeAg-positive chronic hepatitis B patients

Mutants in the basal core promoter (BCP) and precore (PC) regions of hepatitis B virus (HBV) genome are associated with the progression of chronic hepatitis B (CHB) infection. However, quasispecies characteristics of naturally occurring mutants in those regions in HBeAg-positive CHB patients has not...

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Vydáno v:Sci Rep
Hlavní autoři: Yan, Linlin, Zhang, Henghui, Ma, Hui, Liu, Di, Li, Wei, Kang, Yulin, Yang, Ruifeng, Wang, Jianghua, He, Gaixia, Xie, Xingwang, Wang, Hao, Wei, Lai, Lu, Zuhong, Shao, Qixiang, Chen, Hongsong
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673698/
https://ncbi.nlm.nih.gov/pubmed/26647737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17950
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