Genome Replication, Virion Secretion, and e Antigen Expression of Naturally Occurring Hepatitis B Virus Core Promoter Mutants

The core promoter mutants of hepatitis B virus (HBV) emerge as the dominant viral population at the late HBeAg and the anti-HBe stages of HBV infection, with the A1762T/G1764A substitutions as the hotspot mutations. The double core promoter mutations were found by many investigators to moderately en...

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Detalhes bibliográficos
Main Authors: Parekh, Sameer, Zoulim, Fabien, Ahn, Sang Hoon, Tsai, Adrienne, Li, Jisu, Kawai, Shigenobu, Khan, Nasser, Trépo, Christian, Wands, Jack, Tong, Shuping
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC156182/
https://ncbi.nlm.nih.gov/pubmed/12767980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.12.6601-6612.2003
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