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A nuanced role of the small loop of hepatitis B virus small envelope protein in virion morphogenesis and secretion

Abstract Background The virion secretion mechanism of human hepatitis B virus (HBV) remains to be investigated. In our current study, we characterized a reverse transcriptase mutant, which changed from the YMDD motif to YMHA. We noted that this mutant YMHA secreted no virions in the medium. Because...

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Autors principals: Chih-Hsu Chang, Shu-Fan Chou, Chiaho Shih
Format: Artigo
Idioma:Inglês
Publicat: BMC 2021-12-01
Col·lecció:Journal of Biomedical Science
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Accés en línia:https://doi.org/10.1186/s12929-021-00780-0
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