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Alternative lengthening of telomeres can be maintained by preferential elongation of lagging strands
Alternative lengthening of telomeres (ALT) is a telomerase independent telomere maintenance mechanism that occurs in ∼15% of cancers. The potential mechanism of ALT is homology-directed telomere synthesis, but molecular mechanisms of how ALT maintains telomere length in human cancer is poorly unders...
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| Publicat a: | Nucleic Acids Res |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5389697/ https://ncbi.nlm.nih.gov/pubmed/28082393 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1295 |
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