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DNA polymerase δ stalls on telomeric lagging strand templates independently from G-quadruplex formation
Previous evidence indicates that telomeres resemble common fragile sites and present a challenge for DNA replication. The precise impediments to replication fork progression at telomeric TTAGGG repeats are unknown, but are proposed to include G-quadruplexes (G4) on the G-rich strand. Here we examine...
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| Main Authors: | , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3905856/ https://ncbi.nlm.nih.gov/pubmed/24038470 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt813 |
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