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Pif1 is essential for efficient replisome progression through lagging strand G-quadruplex DNA secondary structures
Pif1 DNA helicase is a potent unwinder of G-quadruplex (G4) structures in vitro and functions to maintain genome stability at G4 sequences in Saccharomyces cerevisiae. Here, we developed and utilized a live-cell imaging approach to quantitatively measure the progression rates of single replication f...
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| Published in: | Nucleic Acids Res |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2018
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6294490/ https://ncbi.nlm.nih.gov/pubmed/30395308 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky1065 |
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