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Human Telomeres Maintain Their Overhang Length at Senescence
Normal human cells in culture enter replicative senescence after a finite number of population doublings. The exact molecular mechanisms triggering the growth arrest are poorly understood. A recent report on the disappearance of the G-rich 3′ telomeric overhang in senescent cells led to the hypothes...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
2005
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1061618/ https://ncbi.nlm.nih.gov/pubmed/15743814 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.6.2158-2168.2005 |
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