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Telomere G-overhang Length Measurement: The DSN method

Telomeres terminate in 3´ single stranded G-overhangs that function in telomere end protection and telomerase action. An accurate measurement of overhang length is challenging due to the presence of many kilobases of double-stranded telomere DNA. Here, a simple method is described that utilizes dupl...

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Autores principales: Zhao, Yong, Shay, Jerry W., Wright, Woodring E.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528100/
https://ncbi.nlm.nih.gov/pubmed/21461810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-61779-092-8_5
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