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The roles of WRN and BLM RecQ helicases in the Alternative Lengthening of Telomeres
Approximately 10% of all cancers, but a higher proportion of sarcomas, use the recombination-based alternative lengthening of telomeres (ALT) to maintain telomeres. Two RecQ helicase genes, BLM and WRN, play important roles in homologous recombination repair and they have been implicated in telomeri...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3510502/ https://ncbi.nlm.nih.gov/pubmed/22989712 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks862 |
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