The roles of WRN and BLM RecQ helicases in the Alternative Lengthening of Telomeres

Approximately 10% of all cancers, but a higher proportion of sarcomas, use the recombination-based alternative lengthening of telomeres (ALT) to maintain telomeres. Two RecQ helicase genes, BLM and WRN, play important roles in homologous recombination repair and they have been implicated in telomeri...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Mendez-Bermudez, Aaron, Hidalgo-Bravo, Alberto, Cotton, Victoria E., Gravani, Athanasia, Jeyapalan, Jennie N., Royle, Nicola J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2012
Pynciau:
Genome Integrity, Repair and Replication
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510502/
https://ncbi.nlm.nih.gov/pubmed/22989712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks862
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