The roles of WRN and BLM RecQ helicases in the Alternative Lengthening of Telomeres

Approximately 10% of all cancers, but a higher proportion of sarcomas, use the recombination-based alternative lengthening of telomeres (ALT) to maintain telomeres. Two RecQ helicase genes, BLM and WRN, play important roles in homologous recombination repair and they have been implicated in telomeri...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Mendez-Bermudez, Aaron, Hidalgo-Bravo, Alberto, Cotton, Victoria E., Gravani, Athanasia, Jeyapalan, Jennie N., Royle, Nicola J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2012
Gaiak:
Genome Integrity, Repair and Replication
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510502/
https://ncbi.nlm.nih.gov/pubmed/22989712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks862
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