The roles of WRN and BLM RecQ helicases in the Alternative Lengthening of Telomeres

Approximately 10% of all cancers, but a higher proportion of sarcomas, use the recombination-based alternative lengthening of telomeres (ALT) to maintain telomeres. Two RecQ helicase genes, BLM and WRN, play important roles in homologous recombination repair and they have been implicated in telomeri...

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Detaylı Bibliyografya
Asıl Yazarlar: Mendez-Bermudez, Aaron, Hidalgo-Bravo, Alberto, Cotton, Victoria E., Gravani, Athanasia, Jeyapalan, Jennie N., Royle, Nicola J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2012
Konular:
Genome Integrity, Repair and Replication
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510502/
https://ncbi.nlm.nih.gov/pubmed/22989712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks862
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