The roles of WRN and BLM RecQ helicases in the Alternative Lengthening of Telomeres

Approximately 10% of all cancers, but a higher proportion of sarcomas, use the recombination-based alternative lengthening of telomeres (ALT) to maintain telomeres. Two RecQ helicase genes, BLM and WRN, play important roles in homologous recombination repair and they have been implicated in telomeri...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Mendez-Bermudez, Aaron, Hidalgo-Bravo, Alberto, Cotton, Victoria E., Gravani, Athanasia, Jeyapalan, Jennie N., Royle, Nicola J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2012
Aiheet:
Genome Integrity, Repair and Replication
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510502/
https://ncbi.nlm.nih.gov/pubmed/22989712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks862
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