RecQ-core of BLM unfolds telomeric G-quadruplex in the absence of ATP

Various helicases and single-stranded DNA (ssDNA) binding proteins are known to destabilize G-quadruplex (GQ) structures, which otherwise result in genomic instability. Bulk biochemical studies have shown that Bloom helicase (BLM) unfolds both intermolecular and intramolecular GQ in the presence of...

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Bibliografske podrobnosti
Main Authors: Budhathoki, Jagat B., Ray, Sujay, Urban, Vaclav, Janscak, Pavel, Yodh, Jaya G., Balci, Hamza
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2014
Teme:
Genome Integrity, Repair and Replication
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4191421/
https://ncbi.nlm.nih.gov/pubmed/25245947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku856
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