RPA-Mediated Unfolding of Systematically Varying G-Quadruplex Structures

G-quadruplex (GQ) is a noncanonical nucleic acid structure that is formed by guanine rich sequences. Unless it is destabilized by proteins such as replication protein A (RPA), GQ could interfere with DNA metabolic functions, such as replication or repair. We studied RPA-mediated GQ unfolding using s...

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Detalhes bibliográficos
Main Authors: Ray, Sujay, Qureshi, Mohammad H., Malcolm, Dominic W., Budhathoki, Jagat B., Çelik, Uğur, Balci, Hamza
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2013
Assuntos:
Proteins and Nucleic Acids
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3660638/
https://ncbi.nlm.nih.gov/pubmed/23708363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.04.004
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