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Methylation-sensitive enrichment of minor DNA alleles using a double-strand DNA-specific nuclease
Aberrant methylation changes, often present in a minor allelic fraction in clinical samples such as plasma-circulating DNA (cfDNA), are potentially powerful prognostic and predictive biomarkers in human disease including cancer. We report on a novel, highly-multiplexed approach to facilitate analysi...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5389605/ https://ncbi.nlm.nih.gov/pubmed/27903892 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1166 |
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