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PCR-Based Methods for the Enrichment of Minority Alleles and Mutations
BACKGROUND: The ability to identify low-level somatic DNA mutations and minority alleles within an excess wild-type sample is becoming essential for characterizing early and posttreatment tumor status in cancer patients. Over the past 2 decades, much research has focused on improving the selectivity...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2811432/ https://ncbi.nlm.nih.gov/pubmed/19201784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1373/clinchem.2008.113035 |
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