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COLD-PCR: improving the sensitivity of molecular diagnostics assays

The detection of low-abundance DNA variants or mutations is of particular interest to medical diagnostics, individualized patient treatment and cancer prognosis; however, detection sensitivity for low-abundance variants is a pronounced limitation of most currently available molecular assays. We have...

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Detalhes bibliográficos
Main Authors: Milbury, Coren A, Li, Jin, Liu, Pingfang, Makrigiorgos, G Mike
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3111913/
https://ncbi.nlm.nih.gov/pubmed/21405967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/erm.10.115
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