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Enrichment of Mutations in Multiple DNA Sequences Using COLD-PCR in Emulsion
BACKGROUND: Multiplex detection of low-level mutant alleles in the presence of wild-type DNA would be useful for several fields of medicine including cancer, pre-natal diagnosis and infectious diseases. COLD-PCR is a recently developed method that enriches low-level mutations during PCR cycling, thu...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3516544/ https://ncbi.nlm.nih.gov/pubmed/23236486 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051362 |
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