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PCR-Based Methods for the Enrichment of Minority Alleles and Mutations

BACKGROUND: The ability to identify low-level somatic DNA mutations and minority alleles within an excess wild-type sample is becoming essential for characterizing early and posttreatment tumor status in cancer patients. Over the past 2 decades, much research has focused on improving the selectivity...

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Detalhes bibliográficos
Main Authors: Milbury, Coren A., Li, Jin, Makrigiorgos, G. Mike
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2811432/
https://ncbi.nlm.nih.gov/pubmed/19201784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1373/clinchem.2008.113035
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