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Managing the sequence-specificity of antisense oligonucleotides in drug discovery
All drugs perturb the expression of many genes in the cells that are exposed to them. These gene expression changes can be divided into effects resulting from engaging the intended target and effects resulting from engaging unintended targets. For antisense oligonucleotides, developments in bioinfor...
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| Veröffentlicht in: | Nucleic Acids Res |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5389529/ https://ncbi.nlm.nih.gov/pubmed/28426096 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx056 |
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