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Splice-switching antisense oligonucleotides as therapeutic drugs
Splice-switching oligonucleotides (SSOs) are short, synthetic, antisense, modified nucleic acids that base-pair with a pre-mRNA and disrupt the normal splicing repertoire of the transcript by blocking the RNA–RNA base-pairing or protein–RNA binding interactions that occur between components of the s...
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| Vydáno v: | Nucleic Acids Res |
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| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5001604/ https://ncbi.nlm.nih.gov/pubmed/27288447 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw533 |
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