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Therapeutic correction of ApoER2 splicing in Alzheimer's disease mice using antisense oligonucleotides

Apolipoprotein E receptor 2 (ApoER2) is an apolipoprotein E receptor involved in long‐term potentiation, learning, and memory. Given its role in cognition and its association with the Alzheimer's disease (AD) risk gene, apoE, ApoER2 has been proposed to be involved in AD, though a role for the...

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Detalhes bibliográficos
Publicado no:EMBO Mol Med
Main Authors: Hinrich, Anthony J, Jodelka, Francine M, Chang, Jennifer L, Brutman, Daniella, Bruno, Angela M, Briggs, Clark A, James, Bryan D, Stutzmann, Grace E, Bennett, David A, Miller, Steven A, Rigo, Frank, Marr, Robert A, Hastings, Michelle L
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4818756/
https://ncbi.nlm.nih.gov/pubmed/26902204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201505846
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