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Therapeutic Potential of Splice-Switching Oligonucleotides

Alternative splicing enables a single pre-messenger RNA transcript to yield multiple protein isoforms, making it a major contributor to the diversity of the proteome. While this process is essential for normal development, aberrations in alternative splicing are the cause of a multitude of human dis...

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Bibliografiska uppgifter
Huvudupphovsmän: Bauman, John, Jearawiriyapaisarn, Natee, Kole, Ryszard
Materialtyp: Artigo
Språk:Inglês
Publicerad: Mary Ann Liebert, Inc. 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663420/
https://ncbi.nlm.nih.gov/pubmed/19125639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/oli.2008.0161
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