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Therapeutic potential of antisense oligonucleotides as modulators of alternative splicing
An estimated 60% of all human genes undergo alternative splicing, a highly regulated process that produces splice variants with different functions. Such variants have been linked to a variety of cancers, and genetic diseases such as thalassemia and cystic fibrosis. This Perspective describes a prom...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2003
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC171400/ https://ncbi.nlm.nih.gov/pubmed/12925686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200319547 |
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