Therapeutic potential of antisense oligonucleotides as modulators of alternative splicing
An estimated 60% of all human genes undergo alternative splicing, a highly regulated process that produces splice variants with different functions. Such variants have been linked to a variety of cancers, and genetic diseases such as thalassemia and cystic fibrosis. This Perspective describes a prom...
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| Publié dans: | J Clin Invest |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Clinical Investigation
2003
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171400/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12925686/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI19547 |
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