Identification of Novel Inhibitors of Bacterial Translation Elongation Factors

Bacterial elongation factor Tu (EF-Tu) and EF-Ts are interacting proteins involved in polypeptide chain elongation in protein biosynthesis. A novel scintillation proximity assay for the detection of inhibitors of EF-Tu and EF-Ts, as well as the interaction between them, was developed and used in a h...

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Main Authors: Jayasekera, Maithri M. K., Onheiber, Keysha, Keith, John, Venkatesan, Hariharan, Santillan, Alejandro, Stocking, Emily M., Tang, Liu, Miller, Jennifer, Gomez, Leslie, Rhead, Brooke, Delcamp, Tavner, Huang, Shaoming, Wolin, Ronald, Bobkova, Ekaterina V., Shaw, Karen Joy
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Mechanisms of Action: Physiological Effects
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC538871/
https://ncbi.nlm.nih.gov/pubmed/15616286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.1.131-136.2005
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