Identification of Novel Inhibitors of Bacterial Translation Elongation Factors

Bacterial elongation factor Tu (EF-Tu) and EF-Ts are interacting proteins involved in polypeptide chain elongation in protein biosynthesis. A novel scintillation proximity assay for the detection of inhibitors of EF-Tu and EF-Ts, as well as the interaction between them, was developed and used in a h...

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Detalhes bibliográficos
Main Authors: Jayasekera, Maithri M. K., Onheiber, Keysha, Keith, John, Venkatesan, Hariharan, Santillan, Alejandro, Stocking, Emily M., Tang, Liu, Miller, Jennifer, Gomez, Leslie, Rhead, Brooke, Delcamp, Tavner, Huang, Shaoming, Wolin, Ronald, Bobkova, Ekaterina V., Shaw, Karen Joy
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Mechanisms of Action: Physiological Effects
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC538871/
https://ncbi.nlm.nih.gov/pubmed/15616286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.1.131-136.2005
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