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Identification of Novel Inhibitors of Bacterial Translation Elongation Factors

Bacterial elongation factor Tu (EF-Tu) and EF-Ts are interacting proteins involved in polypeptide chain elongation in protein biosynthesis. A novel scintillation proximity assay for the detection of inhibitors of EF-Tu and EF-Ts, as well as the interaction between them, was developed and used in a h...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Jayasekera, Maithri M. K., Onheiber, Keysha, Keith, John, Venkatesan, Hariharan, Santillan, Alejandro, Stocking, Emily M., Tang, Liu, Miller, Jennifer, Gomez, Leslie, Rhead, Brooke, Delcamp, Tavner, Huang, Shaoming, Wolin, Ronald, Bobkova, Ekaterina V., Shaw, Karen Joy
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC538871/
https://ncbi.nlm.nih.gov/pubmed/15616286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.1.131-136.2005
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