Identification of Novel Inhibitors of Bacterial Translation Elongation Factors

Bacterial elongation factor Tu (EF-Tu) and EF-Ts are interacting proteins involved in polypeptide chain elongation in protein biosynthesis. A novel scintillation proximity assay for the detection of inhibitors of EF-Tu and EF-Ts, as well as the interaction between them, was developed and used in a h...

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Autors principals: Jayasekera, Maithri M. K., Onheiber, Keysha, Keith, John, Venkatesan, Hariharan, Santillan, Alejandro, Stocking, Emily M., Tang, Liu, Miller, Jennifer, Gomez, Leslie, Rhead, Brooke, Delcamp, Tavner, Huang, Shaoming, Wolin, Ronald, Bobkova, Ekaterina V., Shaw, Karen Joy
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
Matèries:
Mechanisms of Action: Physiological Effects
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC538871/
https://ncbi.nlm.nih.gov/pubmed/15616286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.1.131-136.2005
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