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Translation Elongation Factor 2 Is Part of the Target for a New Family of Antifungals

Translation elongation factor 2 (EF2), which in Saccharomyces cerevisiae is expressed from the EFT1 and EFT2 genes, has been found to be targeted by a new family of highly specific antifungal compounds derived from the natural product sordarin. Two complementation groups of mutants resistant to the...

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Detalhes bibliográficos
Main Authors: Capa, Laura, Mendoza, Alfonso, Lavandera, José L., Gómez de las Heras, Federico, García-Bustos, José F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC105921/
https://ncbi.nlm.nih.gov/pubmed/9756779
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