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Sordarins: A New Class of Antifungals with Selective Inhibition of the Protein Synthesis Elongation Cycle in Yeasts

GR135402, a sordarin derivative, was isolated in an antifungal screening program. GR135402, sordarin, and derivatives of both compounds were evaluated for their ability to inhibit cell-free translational systems from five different pathogenic fungi (Candida albicans, Candida glabrata, Candida krusei...

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Bibliographische Detailangaben
Hauptverfasser: Domínguez, Juan Manuel, Kelly, Valerie A., Kinsman, Oonagh S., Marriott, Michael S., Gómez de las Heras, Federico, Martín, J. Julio
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 1998
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC105812/
https://ncbi.nlm.nih.gov/pubmed/9736548
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