Activities of Sordarins in Murine Histoplasmosis

Sordarins are new antifungals which inhibit fungal protein synthesis by blocking elongation factor 2. Three compounds were evaluated in a murine model of histoplasmosis. Immune-competent mice were infected intravenously with 10(6) to 10(8) CFU of Histoplasma capsulatum yeast cells. Mice were treated...

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Библиографические подробности
Главные авторы: Graybill, John R., Najvar, Laura, Fothergill, Annette, Bocanegra, Rosie, de las Heras, Federico Gomez
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 1999
Предметы:
Experimental Therapeutics
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC89349/
https://ncbi.nlm.nih.gov/pubmed/10390228
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