Activities of Sordarins in Murine Histoplasmosis

Sordarins are new antifungals which inhibit fungal protein synthesis by blocking elongation factor 2. Three compounds were evaluated in a murine model of histoplasmosis. Immune-competent mice were infected intravenously with 10(6) to 10(8) CFU of Histoplasma capsulatum yeast cells. Mice were treated...

Full beskrivning

Bibliografiska uppgifter

I publikationen:	Antimicrob Agents Chemother
Huvudupphov:	Graybill, John R., Najvar, Laura, Fothergill, Annette, Bocanegra, Rosie, de las Heras, Federico Gomez
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	American Society for Microbiology (ASM) 1999
Ämnen:	Experimental Therapeutics
Länkar:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89349/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10390228/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.7.1716
Taggar:	Lägg till en tagg Inga taggar, Lägg till första taggen!