Modified mRNA vaccines protect against Zika virus infection

The emergence of ZIKV infection has prompted a global effort to develop safe and effective vaccines. We engineered a lipid nanoparticle (LNP) encapsulated modified mRNA vaccine encoding wild-type or variant ZIKV structural genes and tested immunogenicity and protection in mice. Two doses of modified...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Cell
Asıl Yazarlar: Richner, Justin M., Himansu, Sunny, Dowd, Kimberly A., Butler, Scott, Salazar, Vanessa, Fox, Julie M., Julander, Justin G., Tang, William W., Shresta, Sujan, Pierson, Theodore C., Ciaramella, Giuseppe, Diamond, Michael S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5388441/
https://ncbi.nlm.nih.gov/pubmed/28222903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.02.017
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