Protective Efficacy of Nucleic Acid Vaccines Against Transmission of Zika Virus During Pregnancy in Mice

Zika virus (ZIKV) caused an epidemic of congenital malformations in 2015–2016. Although many vaccine candidates have been generated, few have demonstrated efficacy against congenital ZIKV infection. Here, we evaluated lipid-encapsulated messenger RNA (mRNA) vaccines and a DNA plasmid vaccine encodin...

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Dades bibliogràfiques
Publicat a:J Infect Dis
Autors principals: Jagger, Brett W, Dowd, Kimberly A, Chen, Rita E, Desai, Pritesh, Foreman, Bryant, Burgomaster, Katherine E, Himansu, Sunny, Kong, Wing-Pui, Graham, Barney S, Pierson, Theodore C, Diamond, Michael S
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
Matèries:
Major Articles and Brief Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6782106/
https://ncbi.nlm.nih.gov/pubmed/31260518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiz338
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