Protective Efficacy of Nucleic Acid Vaccines Against Transmission of Zika Virus During Pregnancy in Mice

Zika virus (ZIKV) caused an epidemic of congenital malformations in 2015–2016. Although many vaccine candidates have been generated, few have demonstrated efficacy against congenital ZIKV infection. Here, we evaluated lipid-encapsulated messenger RNA (mRNA) vaccines and a DNA plasmid vaccine encodin...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Jagger, Brett W, Dowd, Kimberly A, Chen, Rita E, Desai, Pritesh, Foreman, Bryant, Burgomaster, Katherine E, Himansu, Sunny, Kong, Wing-Pui, Graham, Barney S, Pierson, Theodore C, Diamond, Michael S
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6782106/
https://ncbi.nlm.nih.gov/pubmed/31260518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiz338
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