Protective Efficacy of Nucleic Acid Vaccines Against Transmission of Zika Virus During Pregnancy in Mice

Zika virus (ZIKV) caused an epidemic of congenital malformations in 2015–2016. Although many vaccine candidates have been generated, few have demonstrated efficacy against congenital ZIKV infection. Here, we evaluated lipid-encapsulated messenger RNA (mRNA) vaccines and a DNA plasmid vaccine encodin...

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Bibliographische Detailangaben
Veröffentlicht in:J Infect Dis
Hauptverfasser: Jagger, Brett W, Dowd, Kimberly A, Chen, Rita E, Desai, Pritesh, Foreman, Bryant, Burgomaster, Katherine E, Himansu, Sunny, Kong, Wing-Pui, Graham, Barney S, Pierson, Theodore C, Diamond, Michael S
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2019
Schlagworte:
Major Articles and Brief Reports
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6782106/
https://ncbi.nlm.nih.gov/pubmed/31260518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiz338
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