2904. Protective Efficacy of Nucleic Acid Vaccines Against Transmission of Zika Virus During Pregnancy in Mice

BACKGROUND: Zika virus (ZIKV) caused an epidemic of microcephaly and congenital malformations in 2015–2016, prompting the development of ZIKV vaccines. Plasmid DNA and modified mRNA lipid nanoparticle-encapsulated (mRNA-LNP) vaccines were among the first to reach human clinical trials, where their e...

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Udgivet i:Open Forum Infect Dis
Main Authors: Jagger, Brett W, Dowd, Kimberly A, Chen, Rita, Desai, Pritesh, Himansu, Sunny, Graham, Barney S, Pierson, Theodore C, Diamond, Michael S
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
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Abstracts
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6808673/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofz359.182
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