Modified mRNA vaccines protect against Zika virus infection

The emergence of ZIKV infection has prompted a global effort to develop safe and effective vaccines. We engineered a lipid nanoparticle (LNP) encapsulated modified mRNA vaccine encoding wild-type or variant ZIKV structural genes and tested immunogenicity and protection in mice. Two doses of modified...

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Bibliografski detalji
Izdano u:Cell
Glavni autori: Richner, Justin M., Himansu, Sunny, Dowd, Kimberly A., Butler, Scott, Salazar, Vanessa, Fox, Julie M., Julander, Justin G., Tang, William W., Shresta, Sujan, Pierson, Theodore C., Ciaramella, Giuseppe, Diamond, Michael S.
Format: Artigo
Jezik:Inglês
Izdano: 2017
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5388441/
https://ncbi.nlm.nih.gov/pubmed/28222903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.02.017
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