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Selective RNA targeting and regulated signaling by RIG-I is controlled by coordination of RNA and ATP binding

RIG-I is an innate immune receptor that detects and responds to infection by deadly RNA viruses such as influenza, and Hepatitis C. In the cytoplasm, RIG-I is faced with a difficult challenge: it must sensitively detect viral RNA while ignoring the abundance of host RNA. It has been suggested that R...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nucleic Acids Res
Egile Nagusiak: Fitzgerald, Megan E., Rawling, David C., Potapova, Olga, Ren, Xiaoming, Kohlway, Andrew, Pyle, Anna Marie
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2017
Gaiak:
RNA
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5388420/
https://ncbi.nlm.nih.gov/pubmed/28180316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw816
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