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Selective RNA targeting and regulated signaling by RIG-I is controlled by coordination of RNA and ATP binding
RIG-I is an innate immune receptor that detects and responds to infection by deadly RNA viruses such as influenza, and Hepatitis C. In the cytoplasm, RIG-I is faced with a difficult challenge: it must sensitively detect viral RNA while ignoring the abundance of host RNA. It has been suggested that R...
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| Publicado no: | Nucleic Acids Res |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5388420/ https://ncbi.nlm.nih.gov/pubmed/28180316 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw816 |
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