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Establishing the role of ATP for the function of the RIG-I innate immune sensor
Retinoic acid-inducible gene I (RIG-I) initiates a rapid innate immune response upon detection and binding to viral ribonucleic acid (RNA). This signal activation occurs only when pathogenic RNA is identified, despite the ability of RIG-I to bind endogenous RNA while surveying the cytoplasm. Here we...
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| Published in: | eLife |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
eLife Sciences Publications, Ltd
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4622095/ https://ncbi.nlm.nih.gov/pubmed/26371557 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.09391 |
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