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Salt-mediated two-site ligand binding by the cocaine-binding aptamer

Multisite ligand binding by proteins is commonly utilized in the regulation of biological systems and exploited in a range of biochemical technologies. Aptamers, although widely utilized in many rationally designed biochemical systems, are rarely capable of multisite ligand binding. The cocaine-bind...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Neves, Miguel A.D., Slavkovic, Sladjana, Churcher, Zachary R., Johnson, Philip E.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5388413/
https://ncbi.nlm.nih.gov/pubmed/28025391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1294
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