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New insights into a classic aptamer: binding sites, cooperativity and more sensitive adenosine detection

The DNA aptamer for adenosine (also for AMP and ATP) is a highly conserved sequence that has recurred in a few selections. It it a widely used model aptamer for biosensor development, and its nuclear magnetic resonance structure shows that each aptamer binds two AMP molecules. In this work, each bin...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Zhang, Zijie, Oni, Olatunji, Liu, Juewen
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737652/
https://ncbi.nlm.nih.gov/pubmed/28591844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx517
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