Kynurenine Pathway Activation in Human African Trypanosomiasis

BACKGROUND. The kynurenine pathway of tryptophan oxidation is associated with central nervous system (CNS) inflammatory pathways. Inhibition of this pathway ameliorates CNS inflammation in rodent models of the late (meningoencephalitic) stage of human African trypanosomiasis (HAT). In this study, we...

Full description

Saved in:
Bibliographic Details
Published in:J Infect Dis
Main Authors: Sternberg, Jeremy M., Forrest, Caroline M., Dalton, R. Neil, Turner, Charles, Rodgers, Jean, Stone, Trevor W., Kennedy, Peter G. E.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2017
Subjects:
Major Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5388295/
https://ncbi.nlm.nih.gov/pubmed/28013248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiw623
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items